HELX
Franklin Genomic Advancements ETF
HELX is an actively managed portfolio of global equity securities of companies relevant to genomic discovery.
Global
EQUITY
Active
MANAGEMENT STYLE
$ 33.7 M
ASSETS UNDER MGMT
50 bp
EXPENSES
Fund Basics
| Inception date | Feb 25, 2020 |
| Regulation | Open-Ended Fund |
| Fund Website | link... |
| Distributions | Annually |
| Currency | USD |
| Holdings Transparency | Full |
| Derivatives-based | No |
| Options available | Yes |
| Currency hedged | No |
| Fund of funds | No |
Top 10 Holdings
| NATERA INC | 10.0 % |
| GUARDANT HEALTH, INC. | 9.5 % |
| KRYSTAL BIOTECH, INC. | 5.0 % |
| LIGAND PHARMACEUTICALS-CL B | 4.5 % |
| ADAPTIVE BIOTECHNOLOGIES CORP. | 4.4 % |
| TWIST BIOSCIENCE CORP. | 4.1 % |
| BRIDGEBIO PHARMA, INC. | 3.1 % |
| VERTEX PHARMACEUTICALS INC | 2.7 % |
| MEDPACE HOLDINGS, INC. | 2.7 % |
| UNITED THERAPEUTICS CORP | 2.7 % |
Constituent Breakdown
| Number of holdings | 72 |
| Herfindahl-Hirschman Index | 386 |
| Wgt avg mkt cap (mns) | $55,646 |
| Large cap (>$10bn) | 62.6% |
| Mid cap ($2-10bn) | 28.6% |
| Small cap (<$2bn) | 3.4% |
| Developed mkts. | 96.3% |
| Emerging mkts. | 1.1% |
Sector Breakdown
Country Exposure
 |
UNITED STATES | 88.7 % |
 |
GERMANY | 2.0 % |
 |
NETHERLANDS | 1.5 % |
 |
IRELAND | 1.2 % |
 |
BRITAIN | 1.0 % |
 |
SOUTH KOREA | 0.9 % |
 |
DENMARK | 0.9 % |
 |
SWITZERLAND | 0.8 % |
Historical Performance
Standardized Performance (as of 09/30/2026)
| YTD | 1 YR | 2 YR | 3 YR | 5 YR | 10 YR | 20 YR | Incep. | |
|---|---|---|---|---|---|---|---|---|
| Price Returns | 22.7% | 44.0% | 17.3% | 16.3% | -3.2% | -- | -- | 9.9% |
| Dividend Yield | 0.0% | 0.6% | 0.2% | 0.2% | 0.1% | -- | -- | 0.1% |
| Total Returns | 22.7% | 44.5% | 17.5% | 16.4% | -3.0% | -- | -- | 10.0% | Ann. Volatility | 24.5% | 23.2% | 23.5% | 21.9% | 24.0% | -- | -- | 27.3% |
Market Correlations
| versus... | Beta | R-squared |
| S&P 500 | 0.92 | 26% |
| MSCI EAFE | 0.78 | 28% |
| MSCI Emg Mkts | 0.38 | 17% |
Liquidity Measures
| Avg. volume (000) | 8 |
| ADV traded (mns) | $0 |
| Turnover | 1.0% |
| Avg. Bid/Ask (% of price) | 0.40% |
Technical Indicators
| 30d moving avg. (EMA) | $43.36 |
| Relative strength (RSI) | 55 |
| MACD/Signal | 0.54/0.36 |
| Bollinger Bands (Upper/Lower) | $45.77/$40.46 |
| Short interest (% of AUM) | 0.5% |
Distributions
Top Ten Comparable ETFs only shown here. For an extended list become an Individual or Professional subscriber. Start your FREE trial
Comparable ETFs Based on Overlap
| Ticker | Fund Name | Overlap vs. HELX |
Expenses vs. HELX |
ALTAR Score™ vs. HELX |
|---|---|---|---|---|
| WDNA | WisdomTree BioRevolution Fund | 31.9% | -5 bp | +0.4% |
| HTEC | ROBO Global Healthcare Technology and Innovation ETF | 29.8% | +30 bp | +2.6% |
| GNOM | Global X Genomics & Biotechnology ETF | 29.3% | 0 bp | -1.0% |
| EKG | First Trust Nasdaq Lux Digital Health Solutions ETF | 26.5% | +15 bp | +1.1% |
| IBB | iShares Biotechnology ETF | 26.3% | -6 bp | +0.6% |
| XBI | State Street SPDR S&P Biotech ETF | 26.0% | -15 bp | -1.5% |
| GNMX | Corgi Genomics & Precision Medicine ETF | 24.9% | -15 bp | -1.1% |
| ARKG | ARK Genomic Revolution ETF | 24.8% | +25 bp | -0.1% |
| IBBQ | Invesco Nasdaq Biotechnology ETF | 24.6% | -31 bp | +0.9% |
| PTH | Invesco Dorsey Wright Healthcare Momentum ETF | 24.3% | +24 bp | -0.4% |
Risk and Returns: HELX vs. Comps (1 YR)
Notes: Top 10 overlapping ETFs. Funds with insufficient history not shown. Some funds may overlap. Hover over data point for ticker symbol.
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Results & Estimates (USD)
| 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | 2027 | ||
|---|---|---|---|---|---|---|---|---|---|
| Sales per share | -- | -- | -- | -- | -- | -- | -- | ||
| change (%) | -- | -- | -- | -- | -- | -- | -- | ||
| Earnings per share | -- | -- | -- | -- | -- | -- | -- | ||
| change (%) | -- | -- | -- | -- | -- | -- | -- | ||
| Dividends per share | -- | -- | -- | -- | -- | -- | -- | ||
| change (%) | -- | -- | -- | -- | -- | -- | -- | ||
| Book value per share | -- | -- | -- | -- | -- | -- | -- | ||
| change (%) | -- | -- | -- | -- | -- | -- | -- |
Return on Equity
Net Margins
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Valuation Metrics
| Fwd Est | 2025 | 2026 | 2027 | |
| Price-to-sales | --x | --x | --x | --x |
| Price-to-earnings | --x | --x | --x | --x |
| Price-to-cash flow | --x | --x | --x | --x |
| Price-to-growth | --x | --x | --x | --x |
| Price-to-book value | --x | --x | --x | --x |
| Yield | --% | --% | --x | --% |
Based on closing prices from 11/6/2026
Peer Group Comparison
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Historical Valuation Trends Sample data. Subscribe for access.
Notes: Based on adjusted historical results for current fund constituents. May differ from results achieved by past fund constituents. Max P/E of 100x.
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ETF Research Center Rating
-1.3%
ALTAR SCORE™
1st
PERCENTILE
AVOID
ETFRC RATING
There are 746 funds in the Global Equity category with an average
ALTAR Score™ of 4.8% and a standard deviation
of 2.6%. HELX's ALTAR Score™ is approximately -2.3 standard
deviations above the category average. This places HELX in the 1st percentile
among funds in the category.
Sell-Side Consensus
$52.85
PRICE TARGET
+25.7%
UPSIDE